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A novel role for the anti-senescence factor TBX2 in DNA repair and cisplatin resistance

The emergence of drug resistant tumours that are able to escape cell death pose a major problem in the treatment of cancers. Tumours develop resistance to DNA-damaging chemotherapeutic agents by acquiring the ability to repair their DNA. Combination therapies that induce DNA damage and disrupt the D...

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Detalles Bibliográficos
Autores principales: Wansleben, S, Davis, E, Peres, J, Prince, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824674/
https://www.ncbi.nlm.nih.gov/pubmed/24113180
http://dx.doi.org/10.1038/cddis.2013.365