Cargando…
CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia
Induced pluripotent stem cells (iPSC) offer a unique opportunity for developmental studies, disease modeling and regenerative medicine approaches in humans. The aim of our study was to create an in vitro ‘patient-specific cell-based system' that could facilitate the screening of new therapeutic...
Autores principales: | Di Pasquale, E, Lodola, F, Miragoli, M, Denegri, M, Avelino-Cruz, J E, Buonocore, M, Nakahama, H, Portararo, P, Bloise, R, Napolitano, C, Condorelli, G, Priori, S G |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824678/ https://www.ncbi.nlm.nih.gov/pubmed/24113177 http://dx.doi.org/10.1038/cddis.2013.369 |
Ejemplares similares
-
Adeno-associated virus-mediated CASQ2 delivery rescues phenotypic alterations in a patient-specific model of recessive catecholaminergic polymorphic ventricular tachycardia
por: Lodola, Francesco, et al.
Publicado: (2016) -
CaMKII-Dependent Contractile Dysfunction and Pro-Arrhythmic Activity in a Mouse Model of Obstructive Sleep Apnea
por: Hegner, Philipp, et al.
Publicado: (2023) -
Flecainide is associated with a reduction in arrhythmic events in a large cohort of patients with catecholaminergic polymorphic ventricular tachycardia
por: Bergeman, A T, et al.
Publicado: (2023) -
CaMKII points the way
por: Leslie, Mitch
Publicado: (2012) -
CaMKII in Cardiometabolic Disease
por: Ozcan, Lale, et al.
Publicado: (2014)