Multisite phosphorylation of c-Jun at threonine 91/93/95 triggers the onset of c-Jun pro-apoptotic activity in cerebellar granule neurons

Cerebellar granule cell (CGC) apoptosis by trophic/potassium (TK) deprivation is a model of election to study the interplay of pro-apoptotic and pro-survival signaling pathways in neuronal cell death. In this model, the c-Jun N-terminal kinase (JNK) induces pro-apoptotic genes through the c-Jun/acti...

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Detalles Bibliográficos
Autores principales: Reddy, C E, Albanito, L, De Marco, P, Aiello, D, Maggiolini, M, Napoli, A, Musti, A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824690/
https://www.ncbi.nlm.nih.gov/pubmed/24113186
http://dx.doi.org/10.1038/cddis.2013.381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824690/
https://www.ncbi.nlm.nih.gov/pubmed/24113186
http://dx.doi.org/10.1038/cddis.2013.381

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