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Multisite phosphorylation of c-Jun at threonine 91/93/95 triggers the onset of c-Jun pro-apoptotic activity in cerebellar granule neurons
Cerebellar granule cell (CGC) apoptosis by trophic/potassium (TK) deprivation is a model of election to study the interplay of pro-apoptotic and pro-survival signaling pathways in neuronal cell death. In this model, the c-Jun N-terminal kinase (JNK) induces pro-apoptotic genes through the c-Jun/acti...
Autores principales: | Reddy, C E, Albanito, L, De Marco, P, Aiello, D, Maggiolini, M, Napoli, A, Musti, A M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824690/ https://www.ncbi.nlm.nih.gov/pubmed/24113186 http://dx.doi.org/10.1038/cddis.2013.381 |
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