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Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation

Epithelial ovarian carcinoma is characterized by high frequency of recurrence (70% of patients) and carboplatin resistance acquisition. Carcinoma-associated mesenchymal stem cells (CA-MSC) have been shown to induce ovarian cancer chemoresistance through trogocytosis. Here we examined CA-MSC properti...

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Detalles Bibliográficos
Autores principales: Castells, M, Milhas, D, Gandy, C, Thibault, B, Rafii, A, Delord, J-P, Couderc, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824693/
https://www.ncbi.nlm.nih.gov/pubmed/24176845
http://dx.doi.org/10.1038/cddis.2013.384