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Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation
Epithelial ovarian carcinoma is characterized by high frequency of recurrence (70% of patients) and carboplatin resistance acquisition. Carcinoma-associated mesenchymal stem cells (CA-MSC) have been shown to induce ovarian cancer chemoresistance through trogocytosis. Here we examined CA-MSC properti...
Autores principales: | Castells, M, Milhas, D, Gandy, C, Thibault, B, Rafii, A, Delord, J-P, Couderc, B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824693/ https://www.ncbi.nlm.nih.gov/pubmed/24176845 http://dx.doi.org/10.1038/cddis.2013.384 |
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