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Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity

Nonobese diabetic (NOD) mice congenic for C57BL/10 (B10)-derived genes in the Idd9 region of chromosome 4 are highly protected from type 1 diabetes (T1D). Idd9 has been divided into three protective subregions (Idd9.1, 9.2, and 9.3), each of which partially prevents disease. In this study we have fi...

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Detalles Bibliográficos
Autores principales: Hamilton-Williams, Emma E., Rainbow, Daniel B., Cheung, Jocelyn, Christensen, Mikkel, Lyons, Paul A., Peterson, Laurence B., Steward, Charles A., Sherman, Linda A., Wicker, Linda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824839/
https://www.ncbi.nlm.nih.gov/pubmed/23934554
http://dx.doi.org/10.1007/s00335-013-9466-y