Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines

Our previous study has revealed that dioscin, a compound with anti-inflammatory, lipid-lowering, anticancer and hepatoprotective effects, may induce autophagy in hepatoma cells. Autophagy is a lysosomal degradation pathway that is essential for cell survival and tissue homeostasis. In this study, th...

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Detalles Bibliográficos
Autores principales: Hsieh, Ming-Ju, Tsai, Te-Lung, Hsieh, Yih-Shou, Wang, Chau-Jong, Chiou, Hui-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Molecular Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824840/
https://www.ncbi.nlm.nih.gov/pubmed/23552851
http://dx.doi.org/10.1007/s00204-013-1047-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824840/
https://www.ncbi.nlm.nih.gov/pubmed/23552851
http://dx.doi.org/10.1007/s00204-013-1047-z

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