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Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines
Our previous study has revealed that dioscin, a compound with anti-inflammatory, lipid-lowering, anticancer and hepatoprotective effects, may induce autophagy in hepatoma cells. Autophagy is a lysosomal degradation pathway that is essential for cell survival and tissue homeostasis. In this study, th...
Autores principales: | Hsieh, Ming-Ju, Tsai, Te-Lung, Hsieh, Yih-Shou, Wang, Chau-Jong, Chiou, Hui-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824840/ https://www.ncbi.nlm.nih.gov/pubmed/23552851 http://dx.doi.org/10.1007/s00204-013-1047-z |
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