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Relationship between vascular reactivity and expression of HMGB1 in a rat model of septic aorta

INTRUODUCTION: High mobility group box 1 (HMGB1), a ubiquitous nuclear protein, induces several inflammatory diseases and functions as a fatal factor when released extracellularly. The effect of HMGB1 on vascular reactivity during sepsis remains to be clarified. METHODS: A rat model of abdominal sep...

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Detalles Bibliográficos
Autores principales: Nishiike, Satoshi, Hiramatsu, Toshiaki, Shiraishi, Miharu, Ueda, Yoshimichi, Tsuchida, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824914/
https://www.ncbi.nlm.nih.gov/pubmed/23532259
http://dx.doi.org/10.1007/s00540-013-1584-x