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Folic Acid-Chitosan Conjugated Nanoparticles for Improving Tumor-Targeted Drug Delivery

Objective. To prepare folic acid-chitosan conjugated nanoparticles (FA-CS NPs) and evaluate their targeting specificity on tumor cells. Methods. Chitosan (CS) NPs were prepared by ionic cross linking method, and folic acid (FA) was conjugated with CS NPs by electrostatic interaction. The properties...

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Detalles Bibliográficos
Autores principales: Song, Huijuan, Su, Chang, Cui, Wenyu, Zhu, Bingya, Liu, Liwei, Chen, Zhenhua, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825055/
https://www.ncbi.nlm.nih.gov/pubmed/24282819
http://dx.doi.org/10.1155/2013/723158