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High-Resolution Melting Curve Analysis for High-Throughput Genotyping of NOD2/CARD15 Mutations and Distribution of These Mutations in Slovenian Inflammatory Bowel Diseases Patients

Inflammatory bowel diseases (IBD) are usually classified into Crohn's disease (CD) and ulcerative colitis (UC). NOD2/CARD15 was the first identified CD-susceptibility gene and was confirmed as the most potent disease gene in CD pathogenesis. Three NOD2/CARD15 variants, namely two missense polym...

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Detalles Bibliográficos
Autores principales: Mitrovič, Mitja, Potočnik, Uroš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825075/
https://www.ncbi.nlm.nih.gov/pubmed/21734346
http://dx.doi.org/10.3233/DMA-2011-0783