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Identification of the Ca(2+) entry pathway involved in deoxygenation-induced phosphatidylserine exposure in red blood cells from patients with sickle cell disease

Phosphatidylserine (PS) exposure in red blood cells (RBCs) from sickle cell disease (SCD) patients is increased compared to levels in normal individuals and may participate in the anaemic and ischaemic complications of SCD. Exposure is increased by deoxygenation and occurs with elevation of intracel...

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Detalles Bibliográficos
Autores principales: Cytlak, U. M., Hannemann, A., Rees, D. C., Gibson, J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825215/
https://www.ncbi.nlm.nih.gov/pubmed/23775402
http://dx.doi.org/10.1007/s00424-013-1308-y