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Processing of Damaged DNA Ends for Double-Strand Break Repair in Mammalian Cells

Most DNA double-strand breaks (DSBs) formed in a natural environment have chemical modifications at or near the ends that preclude direct religation and require removal or other processing so that rejoining can proceed. Free radical-mediated DSBs typically bear unligatable 3′-phosphate or 3′-phospho...

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Detalles Bibliográficos
Autor principal: Povirk, Lawrence F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825254/
https://www.ncbi.nlm.nih.gov/pubmed/24236237
http://dx.doi.org/10.5402/2012/345805