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Processing of Damaged DNA Ends for Double-Strand Break Repair in Mammalian Cells
Most DNA double-strand breaks (DSBs) formed in a natural environment have chemical modifications at or near the ends that preclude direct religation and require removal or other processing so that rejoining can proceed. Free radical-mediated DSBs typically bear unligatable 3′-phosphate or 3′-phospho...
Autor principal: | Povirk, Lawrence F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825254/ https://www.ncbi.nlm.nih.gov/pubmed/24236237 http://dx.doi.org/10.5402/2012/345805 |
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