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Structural insights into H(+)-coupled multidrug extrusion by a MATE transporter

Multidrug and toxic compound extrusion (MATE) transporters contribute to multidrug resistance by coupling the efflux of drugs to the influx of Na(+) or H(+). Known structures of Na(+)-coupled, extracellular-facing MATE transporters from the NorM subfamily revealed twelve membrane-spanning segments r...

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Detalles Bibliográficos
Autores principales:	Lu, Min, Radchenko, Martha, Symersky, Jindrich, Nie, Rongxin, Guo, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825517/ https://www.ncbi.nlm.nih.gov/pubmed/24141706 http://dx.doi.org/10.1038/nsmb.2687

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