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Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling

ABSTRACT: Renal fibrosis is a common consequence of unilateral ureteral obstruction, which provides a useful model to investigate the pathogenesis of obstructive nephropathy and progressive renal fibrosis. Transforming growth factor (TGF-β1) has been recognized as a key mediator in renal fibrosis by...

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Detalles Bibliográficos
Autores principales: Park, Jinah, Lee, So-Young, Ooshima, Akira, Yang, Kyung-Min, Kang, Jin Muk, Kim, Young-Woong, Kim, Seong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825548/
https://www.ncbi.nlm.nih.gov/pubmed/24072041
http://dx.doi.org/10.1007/s00109-013-1086-1