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Prohibitin (PHB) inhibits apoptosis in rat granulosa cells (GCs) through the extracellular signal-regulated kinase 1/2 (ERK1/2) and the Bcl family of proteins

Mammalian ovarian follicular development is tightly regulated by crosstalk between cell death and survival signals, which include both endocrine and intra-ovarian regulators. Whether the follicle ultimately ovulates or undergoes atresia is dependent on the expression and actions of factors promoting...

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Detalles Bibliográficos
Autores principales: Chowdhury, Indrajit, Thompson, Winston E., Welch, Crystal, Thomas, Kelwyn, Matthews, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825582/
https://www.ncbi.nlm.nih.gov/pubmed/24096434
http://dx.doi.org/10.1007/s10495-013-0901-z