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Role of Autophagy in Glycogen Breakdown and Its Relevance to Chloroquine Myopathy

Several myopathies are associated with defects in autophagic and lysosomal degradation of glycogen, but it remains unclear how glycogen is targeted to the lysosome and what significance this process has for muscle cells. We have established a Drosophila melanogaster model to study glycogen autophagy...

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Detalles Bibliográficos
Autores principales: Zirin, Jonathan, Nieuwenhuis, Joppe, Perrimon, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825659/
https://www.ncbi.nlm.nih.gov/pubmed/24265594
http://dx.doi.org/10.1371/journal.pbio.1001708