Fate of paclitaxel lipid nanocapsules in intestinal mucus in view of their oral delivery

The bioavailability of paclitaxel (Ptx) has previously been improved via its encapsulation in lipid nanocapsules (LNCs). In this work, the interactions between LNCs and intestinal mucus are studied because they are viewed as an important barrier to successful oral delivery. The rheological propertie...

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Detalles Bibliográficos
Autores principales: Groo, Anne-Claire, Saulnier, Patrick, Gimel, Jean-Christophe, Gravier, Julien, Ailhas, Caroline, Benoit, Jean-Pierre, Lagarce, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825687/
https://www.ncbi.nlm.nih.gov/pubmed/24235827
http://dx.doi.org/10.2147/IJN.S51837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825687/
https://www.ncbi.nlm.nih.gov/pubmed/24235827
http://dx.doi.org/10.2147/IJN.S51837

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