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Endothelin Receptor A Blockade Is an Ineffective Treatment for Adriamycin Nephropathy

Endothelin is a vasoconstricting peptide that plays a key role in vascular homeostasis, exerting its biologic effects via two receptors, the endothelin receptor A (ETA) and endothelin receptor B (ETB). Activation of ETA and ETB has opposing actions, in which hyperactive ETA is generally vasoconstric...

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Detalles Bibliográficos
Autores principales: Tan, Roderick J., Zhou, Lili, Zhou, Dong, Lin, Lin, Liu, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825716/
https://www.ncbi.nlm.nih.gov/pubmed/24265790
http://dx.doi.org/10.1371/journal.pone.0079963