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Endothelin Receptor A Blockade Is an Ineffective Treatment for Adriamycin Nephropathy
Endothelin is a vasoconstricting peptide that plays a key role in vascular homeostasis, exerting its biologic effects via two receptors, the endothelin receptor A (ETA) and endothelin receptor B (ETB). Activation of ETA and ETB has opposing actions, in which hyperactive ETA is generally vasoconstric...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825716/ https://www.ncbi.nlm.nih.gov/pubmed/24265790 http://dx.doi.org/10.1371/journal.pone.0079963 |