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The Janus face of cyclophosphamide: A sterile inflammatory response that potentiates cancer immunotherapy

Cyclophosphamide, within well-defined therapeutic regimens, increases the antineoplastic effects of immunotherapy. We have recently identified multiple factors and mechanisms that underlie the paradoxical synergy between these two treatment modalities. In particular, we found that cyclophosphamide s...

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Detalles Bibliográficos
Autores principales: Ziccheddu, Giovanna, Proietti, Enrico, Moschella, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825725/
https://www.ncbi.nlm.nih.gov/pubmed/24244905
http://dx.doi.org/10.4161/onci.25789