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Getting by with a little help from the right CD4(+) T cells
Tumor infiltration by effector cells is essential for the efficacy of T cell-based immunotherapeutic approaches against brain malignancies. We found that tumor-associated antigen (TAA)-specific CD8(+) T cells are optimally recruited to neoplastic lesions when co-administered with T(H)1 polarized CD4...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825730/ https://www.ncbi.nlm.nih.gov/pubmed/24244904 http://dx.doi.org/10.4161/onci.25772 |