Cargando…

Macromolecule Extravasation—Xenograft Size Matters: A Systematic Study Using Probe-Based Confocal Laser Endomicroscopy (pCLE)

PURPOSE: Profound changes of the vasculature in tumors critically impact drug delivery and therapy response. We aimed at developing a procedure to monitor morphological and functional parameters of the vasculature in subcutaneous xenograft models commonly applied for therapy testing by using probe-b...

Descripción completa

Detalles Bibliográficos
Autores principales: Dietrich, Antje, Stewart, James, Huether, Melanie, Helm, Mario, Schuetze, Christina, Schnittler, Hans-Joachim, Jaffray, David A., Kunz-Schughart, Leoni A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826054/
https://www.ncbi.nlm.nih.gov/pubmed/23632953
http://dx.doi.org/10.1007/s11307-013-0641-z