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Macromolecule Extravasation—Xenograft Size Matters: A Systematic Study Using Probe-Based Confocal Laser Endomicroscopy (pCLE)
PURPOSE: Profound changes of the vasculature in tumors critically impact drug delivery and therapy response. We aimed at developing a procedure to monitor morphological and functional parameters of the vasculature in subcutaneous xenograft models commonly applied for therapy testing by using probe-b...
Autores principales: | Dietrich, Antje, Stewart, James, Huether, Melanie, Helm, Mario, Schuetze, Christina, Schnittler, Hans-Joachim, Jaffray, David A., Kunz-Schughart, Leoni A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826054/ https://www.ncbi.nlm.nih.gov/pubmed/23632953 http://dx.doi.org/10.1007/s11307-013-0641-z |
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