Synthesis of Marine α-Methoxylated Fatty Acid Analogs that Effectively Inhibit the Topoisomerase IB from Leishmania donovani with a Mechanism Different from that of Camptothecin

Sponges biosynthesize α-methoxylated fatty acids with unusual biophysical and biological properties and in some cases they display enhanced anticancer activities. However, the antiprotozoal properties of the α-methoxylated fatty acids have been less studied. In this work, we describe the total synth...

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Detalles Bibliográficos
Autores principales: Carballeira, Néstor M., Montano, Nashbly, Alvarez-Velilla, Raquel, Prada, Christopher F., Reguera, Rosa M., Balaña-Fouce, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826128/
https://www.ncbi.nlm.nih.gov/pubmed/24084785
http://dx.doi.org/10.3390/md11103661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826128/
https://www.ncbi.nlm.nih.gov/pubmed/24084785
http://dx.doi.org/10.3390/md11103661

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