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Reestablishment of Ischemia-Reperfusion Liver Injury by N-Acetylcysteine Administration prior to a Preconditioning Iron Protocol

The role of iron (Fe)-induced prooxidant status in Fe preconditioning against ischemia (1 h)-reperfusion (20 h) induced liver injury was assessed using N-acetylcysteine (NAC) (1 g/kg) before Fe (50 mg/kg), given to male Sprague Dawley rats on alternate days during 10 days. IR significantly increased...

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Detalles Bibliográficos
Autores principales: Fernández, Virginia, Vargas, Romina, Castillo, Valentina, Cádiz, Nicolás, Bastías, Daniela, Román, Sebastián, Tapia, Gladys, Videla, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826321/
https://www.ncbi.nlm.nih.gov/pubmed/24288495
http://dx.doi.org/10.1155/2013/607285