The PPARα/γ Agonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid Utilization In Vivo in the Obese Zucker Rat

Metabolic flexibility was assessed in male Zucker rats: lean controls, obese controls, and obese rats treated with the dual peroxisome proliferator activated receptor (PPAR) α/γ agonist, tesaglitazar, 3 μmol/kg/day for 3 weeks. Whole body glucose disposal rate (R (d)) and hepatic glucose output (HGO...

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Detalles Bibliográficos
Autores principales: Wallenius, Kristina, Kjellstedt, Ann, Thalén, Pia, Löfgren, Lars, Oakes, Nicholas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826326/
https://www.ncbi.nlm.nih.gov/pubmed/24285952
http://dx.doi.org/10.1155/2013/305347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826326/
https://www.ncbi.nlm.nih.gov/pubmed/24285952
http://dx.doi.org/10.1155/2013/305347

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