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The PPARα/γ Agonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid Utilization In Vivo in the Obese Zucker Rat
Metabolic flexibility was assessed in male Zucker rats: lean controls, obese controls, and obese rats treated with the dual peroxisome proliferator activated receptor (PPAR) α/γ agonist, tesaglitazar, 3 μmol/kg/day for 3 weeks. Whole body glucose disposal rate (R (d)) and hepatic glucose output (HGO...
Autores principales: | Wallenius, Kristina, Kjellstedt, Ann, Thalén, Pia, Löfgren, Lars, Oakes, Nicholas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826326/ https://www.ncbi.nlm.nih.gov/pubmed/24285952 http://dx.doi.org/10.1155/2013/305347 |
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