Combination of ERG9 Repression and Enzyme Fusion Technology for Improved Production of Amorphadiene in Saccharomyces cerevisiae

The yeast strain (Saccharomyces cerevisiae) MTCC 3157 was selected for combinatorial biosynthesis of plant sesquiterpene amorpha-4,11-diene. Our main objective was to overproduce amorpha 4-11-diene, which is a key precursor molecule of artemisinin (antimalarial drug) produced naturally in plant Arte...

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Detalles Bibliográficos
Autores principales: Baadhe, Rama Raju, Mekala, Naveen Kumar, Parcha, Sreenivasa Rao, Prameela Devi, Yalavarthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826331/
https://www.ncbi.nlm.nih.gov/pubmed/24282652
http://dx.doi.org/10.1155/2013/140469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826331/
https://www.ncbi.nlm.nih.gov/pubmed/24282652
http://dx.doi.org/10.1155/2013/140469

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