Cargando…

Combination of ERG9 Repression and Enzyme Fusion Technology for Improved Production of Amorphadiene in Saccharomyces cerevisiae

The yeast strain (Saccharomyces cerevisiae) MTCC 3157 was selected for combinatorial biosynthesis of plant sesquiterpene amorpha-4,11-diene. Our main objective was to overproduce amorpha 4-11-diene, which is a key precursor molecule of artemisinin (antimalarial drug) produced naturally in plant Arte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baadhe, Rama Raju, Mekala, Naveen Kumar, Parcha, Sreenivasa Rao, Prameela Devi, Yalavarthy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826331/ https://www.ncbi.nlm.nih.gov/pubmed/24282652 http://dx.doi.org/10.1155/2013/140469

Ejemplares similares

Optimization of amorphadiene production in engineered yeast by response surface methodology
por: Baadhe, Rama Raju, et al.
Publicado: (2013)

Physical and degradation properties of PLGA scaffolds fabricated by salt fusion technique
por: Mekala, Naveen Kumar, et al.
Publicado: (2013)

Improved osteogenic differentiation of umbilical cord blood MSCs using custom made perfusion bioreactor
por: Birru, Bhaskar, et al.
Publicado: (2018)

Engineering acetyl-CoA supply and ERG9 repression to enhance mevalonate production in Saccharomyces cerevisiae
por: Wegner, Scott A, et al.
Publicado: (2021)

Glucose repression in Saccharomyces cerevisiae
por: Kayikci, Ömur, et al.
Publicado: (2015)

Dynamic Control of ERG20 and ERG9 Expression for Improved Casbene Production in Saccharomyces cerevisiae
por: Callari, Roberta, et al.
Publicado: (2018)

Chemo- and Diastereoselective Hydrosilylation of Amorphadiene toward the Synthesis of Artemisinin
por: Schwertz, Geoffrey, et al.
Publicado: (2020)

Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae
por: Loney, Esther R, et al.
Publicado: (2009)

Modular co-culture engineering of Yarrowia lipolytica for amorphadiene biosynthesis
por: Marsafari, Monireh, et al.
Publicado: (2022)

Directed evolution of the fusion enzyme for improving astaxanthin biosynthesis in Saccharomyces cerevisiae
por: Ding, Yong-Wen, et al.
Publicado: (2022)

Modelling of glucose repression signalling in yeast Saccharomyces cerevisiae
por: Persson, Sebastian, et al.
Publicado: (2022)

Thermotolerance improvement of engineered Saccharomyces cerevisiae ERG5 Delta ERG4 Delta ERG3 Delta, molecular mechanism, and its application in corn ethanol production
por: Yang, Peizhou, et al.
Publicado: (2023)

Filamentation of Metabolic Enzymes in Saccharomyces cerevisiae
por: Shen, Qing-Ji, et al.
Publicado: (2016)

Debottlenecking mevalonate pathway for antimalarial drug precursor amorphadiene biosynthesis in Yarrowia lipolytica
por: Marsafari, Monireh, et al.
Publicado: (2020)

Condensate Formation by Metabolic Enzymes in Saccharomyces cerevisiae
por: Miura, Natsuko
Publicado: (2022)

High yield purification of full-length functional hERG K(+) channels produced in Saccharomyces cerevisiae
por: Molbaek, Karen, et al.
Publicado: (2015)

Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae
por: Yuan, Jifeng, et al.
Publicado: (2015)

Reconstruction and logical modeling of glucose repression signaling pathways in Saccharomyces cerevisiae
por: Christensen, Tobias S, et al.
Publicado: (2009)

Trehalose-6-phosphate promotes fermentation and glucose repression in Saccharomyces cerevisiae
por: Vicente, Rebeca L., et al.
Publicado: (2018)

Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae
por: Greetham, Darren, et al.
Publicado: (2010)

Fabrication techniques involved in developing the composite scaffolds PCL/HA nanoparticles for bone tissue engineering applications
por: Murugan, Sivasankar, et al.
Publicado: (2021)

Engineering of Multiple Modules to Improve Amorphadiene Production in Bacillus subtilis Using CRISPR-Cas9
por: Song, Yafeng, et al.
Publicado: (2021)

Glucose repression can be alleviated by reducing glucose phosphorylation rate in Saccharomyces cerevisiae
por: Lane, Stephan, et al.
Publicado: (2018)

Repression of mitochondrial metabolism for cytosolic pyruvate-derived chemical production in Saccharomyces cerevisiae
por: Morita, Keisuke, et al.
Publicado: (2019)

Dual regulation of lipid droplet-triacylglycerol metabolism and ERG9 expression for improved β-carotene production in Saccharomyces cerevisiae
por: Bu, Xiao, et al.
Publicado: (2022)

TMPRSS2-ERG fusions confer efficacy of enzalutamide in an in vivo bone tumor growth model
por: Semaan, Louie, et al.
Publicado: (2019)

Improvement of Ethanol Tolerance by Inactive Protoplast Fusion in Saccharomyces cerevisiae
por: Xin, Yi, et al.
Publicado: (2020)

Heterologous production of raspberry ketone in the wine yeast Saccharomyces cerevisiae via pathway engineering and synthetic enzyme fusion
por: Lee, Danna, et al.
Publicado: (2016)

NRG1 is required for glucose repression of the SUC2 and GAL genes of Saccharomyces cerevisiae
por: Zhou, Heng, et al.
Publicado: (2001)

Upregulating the mevalonate pathway and repressing sterol synthesis in Saccharomyces cerevisiae enhances the production of triterpenes
por: Bröker, Jan Niklas, et al.
Publicado: (2018)

The GIS2 Gene Is Repressed by a Zinc-Regulated Bicistronic RNA in Saccharomyces cerevisiae
por: Taggart, Janet, et al.
Publicado: (2018)

MIG1 Glucose Repression in Metabolic Processes of Saccharomyces cerevisiae: Genetics to Metabolic Engineering
por: Alipourfard, Iraj, et al.
Publicado: (2019)

eIF2A represses cell wall biogenesis gene expression in Saccharomyces cerevisiae
por: Meyer, Laura, et al.
Publicado: (2023)

Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
por: Hull, Claire M, et al.
Publicado: (2014)

Dynamic control of ERG20 expression combined with minimized endogenous downstream metabolism contributes to the improvement of geraniol production in Saccharomyces cerevisiae
por: Zhao, Jianzhi, et al.
Publicado: (2017)

Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth
por: Obinata, Daisuke, et al.
Publicado: (2014)

Osmotic Balance Regulates Cell Fusion during Mating in Saccharomyces cerevisiae
por: Philips, Jennifer, et al.
Publicado: (1997)

SNAREs support atlastin-mediated homotypic ER fusion in Saccharomyces cerevisiae
por: Lee, Miriam, et al.
Publicado: (2015)

Neo1 and phosphatidylethanolamine contribute to vacuole membrane fusion in Saccharomyces cerevisiae
por: Wu, Yuantai, et al.
Publicado: (2016)

Chitin synthase 1, an auxiliary enzyme for chitin synthesis in Saccharomyces cerevisiae
Publicado: (1989)

Cannot write session to /tmp/vufind_sessions/sess_4pn333l59q884fvbf7dshmneqa