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Many human accelerated regions are developmental enhancers

The genetic changes underlying the dramatic differences in form and function between humans and other primates are largely unknown, although it is clear that gene regulatory changes play an important role. To identify regulatory sequences with potentially human-specific functions, we and others used...

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Detalles Bibliográficos
Autores principales: Capra, John A., Erwin, Genevieve D., McKinsey, Gabriel, Rubenstein, John L. R., Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826498/
https://www.ncbi.nlm.nih.gov/pubmed/24218637
http://dx.doi.org/10.1098/rstb.2013.0025