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Transcription-factor occupancy at HOT regions quantitatively predicts RNA polymerase recruitment in five human cell lines
BACKGROUND: High-occupancy target (HOT) regions are compact genome loci occupied by many different transcription factors (TFs). HOT regions were initially defined in invertebrate model organisms, and we here show that they are a ubiquitous feature of the human gene-regulation landscape. RESULTS: We...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826616/ https://www.ncbi.nlm.nih.gov/pubmed/24138567 http://dx.doi.org/10.1186/1471-2164-14-720 |