Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

Neurite growth requires two guanine nucleotide-binding protein polymers of tubulins and septins. However, whether and how those cytoskeletal systems are coordinated was unknown. Here we show that the acute knockdown or knockout of the pivotal septin subunit SEPT7 from cerebrocortical neurons impairs...

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Detalles Bibliográficos
Autores principales: Ageta-Ishihara, Natsumi, Miyata, Takaki, Ohshima, Chika, Watanabe, Masahiko, Sato, Yoshikatsu, Hamamura, Yuki, Higashiyama, Tetsuya, Mazitschek, Ralph, Bito, Haruhiko, Kinoshita, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826633/
https://www.ncbi.nlm.nih.gov/pubmed/24113571
http://dx.doi.org/10.1038/ncomms3532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826633/
https://www.ncbi.nlm.nih.gov/pubmed/24113571
http://dx.doi.org/10.1038/ncomms3532

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