Cargando…
Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation
Neurite growth requires two guanine nucleotide-binding protein polymers of tubulins and septins. However, whether and how those cytoskeletal systems are coordinated was unknown. Here we show that the acute knockdown or knockout of the pivotal septin subunit SEPT7 from cerebrocortical neurons impairs...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826633/ https://www.ncbi.nlm.nih.gov/pubmed/24113571 http://dx.doi.org/10.1038/ncomms3532 |