Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy

Cellular responses to DNA damage involve distinct DNA repair pathways, such as mismatch repair (MMR) and base excision repair (BER). Using Caenorhabditis elegans as a model system, we present genetic and molecular evidence of a mechanistic link between processing of DNA damage and activation of auto...

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Detalles Bibliográficos
Autores principales: SenGupta, Tanima, Torgersen, Maria Lyngaas, Kassahun, Henok, Vellai, Tibor, Simonsen, Anne, Nilsen, Hilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826653/
https://www.ncbi.nlm.nih.gov/pubmed/24154628
http://dx.doi.org/10.1038/ncomms3674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826653/
https://www.ncbi.nlm.nih.gov/pubmed/24154628
http://dx.doi.org/10.1038/ncomms3674

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