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Different Desensitization Patterns for Sensory and Vascular TRPV1 Populations in the Rat: Expression, Localization and Functional Consequences

BACKGROUND AND PURPOSE: TRPV1 is expressed in sensory neurons and vascular smooth muscle cells, contributing to both pain perception and tissue blood distribution. Local desensitization of TRPV1 in sensory neurons by prolonged, high dose stimulation is re-engaged in clinical practice to achieve anal...

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Detalles Bibliográficos
Autores principales: Czikora, Ágnes, Rutkai, Ibolya, Pásztor, Enikő T., Szalai, Andrea, Pórszász, Róbert, Boczán, Judit, Édes, István, Papp, Zoltán, Tóth, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826751/
https://www.ncbi.nlm.nih.gov/pubmed/24250792
http://dx.doi.org/10.1371/journal.pone.0078184