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Different Desensitization Patterns for Sensory and Vascular TRPV1 Populations in the Rat: Expression, Localization and Functional Consequences
BACKGROUND AND PURPOSE: TRPV1 is expressed in sensory neurons and vascular smooth muscle cells, contributing to both pain perception and tissue blood distribution. Local desensitization of TRPV1 in sensory neurons by prolonged, high dose stimulation is re-engaged in clinical practice to achieve anal...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826751/ https://www.ncbi.nlm.nih.gov/pubmed/24250792 http://dx.doi.org/10.1371/journal.pone.0078184 |