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Release of tissue inhibitor of metalloproteinase-2 from alginate microcapsule encapsulating genetically engineered cells
BACKGROUND: In this study, 293T cells were genetically engineered to secrete tissue inhibitor of metalloproteinase-2 (TIMP2) and encapsulated into alginate microcapsules to continuously release TIMP2 protein. METHODS: The anti-invasive potential of the microcapsules was studied in vitro using brain...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826773/ https://www.ncbi.nlm.nih.gov/pubmed/24231999 http://dx.doi.org/10.2147/IJN.S52577 |