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Association of the PGC-1α rs8192678 Variant with Microalbuminuria in Subjects with Type 2 Diabetes Mellitus

PPAR-γ co-activator-1α (PGC-1α) is a tissue-specific transcriptional co-activator involved in the regulation of antioxidant enzymes. The A-allele of the rs8192678 PGC-1 α} (G>A) gene variant has previously been associated with nephropathy in Korean and Indian-Asian type 2 diabetes mellitus (T2DM)...

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Detalles Bibliográficos
Autores principales: Prior, Sarah L., Clark, Amy R., Jones, Danielle A., Bain, Steve C., Hurel, Steve J., Humphries, Steve E., Stephens, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826894/
https://www.ncbi.nlm.nih.gov/pubmed/22684233
http://dx.doi.org/10.3233/DMA-2012-0894