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Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis

Excessive production of proinflammatory mediators is observed in patients undergoing hemorrhagic and septic shock. Here, we report the detection of cold-inducible RNA-binding protein (CIRP) in the blood of surgical ICU individuals. In animal models of hemorrhage and sepsis, CIRP is up-regulated in s...

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Detalles Bibliográficos
Autores principales: Qiang, Xiaoling, Yang, Weng-Lang, Wu, Rongqian, Zhou, Mian, Jacob, Asha, Dong, Weifeng, Kuncewitch, Michael, Ji, Youxin, Yang, Huan, Wang, Haichao, Fujita, Jun, Nicastro, Jeffrey, Coppa, Gene F., Tracey, Kevin J., Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826915/
https://www.ncbi.nlm.nih.gov/pubmed/24097189
http://dx.doi.org/10.1038/nm.3368