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The oncogenic TBX3 is a downstream target and mediator of the TGF-β1 signaling pathway
The T-box transcription factor, TBX3, plays an important role in embryonic development, and haploinsufficiency of TBX3 causes ulnar–mammary syndrome. Overexpression of TBX3, on the other hand, is associated with several cancers, and preliminary evidence suggests that increased levels of TBX3 may inh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826994/ https://www.ncbi.nlm.nih.gov/pubmed/24025717 http://dx.doi.org/10.1091/mbc.E13-05-0273 |