Functional Analysis of Hsp70 Inhibitors

The molecular chaperones of the Hsp70 family have been recognized as targets for anti-cancer therapy. Since several paralogs of Hsp70 proteins exist in cytosol, endoplasmic reticulum and mitochondria, we investigated which isoform needs to be down-regulated for reducing viability of cancer cells. Fo...

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Detalles Bibliográficos
Autores principales: Schlecht, Rainer, Scholz, Sebastian R., Dahmen, Heike, Wegener, Ansgar, Sirrenberg, Christian, Musil, Djordje, Bomke, Joerg, Eggenweiler, Hans-Michael, Mayer, Matthias P., Bukau, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827032/
https://www.ncbi.nlm.nih.gov/pubmed/24265689
http://dx.doi.org/10.1371/journal.pone.0078443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827032/
https://www.ncbi.nlm.nih.gov/pubmed/24265689
http://dx.doi.org/10.1371/journal.pone.0078443

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