RB1 Status in Triple Negative Breast Cancer Cells Dictates Response to Radiation Treatment and Selective Therapeutic Drugs

Triple negative breast cancer (TNBC) includes basal-like and claudin-low subtypes for which only chemotherapy and radiation therapy are currently available. The retinoblastoma (RB1) tumor suppressor is frequently lost in human TNBC. Knockdown of RB1 in luminal BC cells was shown to affect response t...

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Detalles Bibliográficos
Autores principales: Robinson, Tyler J. W., Liu, Jeff C., Vizeacoumar, Frederick, Sun, Thomas, Maclean, Neil, Egan, Sean E., Schimmer, Aaron D., Datti, Alessandro, Zacksenhaus, Eldad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827056/
https://www.ncbi.nlm.nih.gov/pubmed/24265703
http://dx.doi.org/10.1371/journal.pone.0078641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827056/
https://www.ncbi.nlm.nih.gov/pubmed/24265703
http://dx.doi.org/10.1371/journal.pone.0078641

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