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Solution Scattering and FRET Studies on Nucleosomes Reveal DNA Unwrapping Effects of H3 and H4 Tail Removal

Using a combination of small-angle X-ray scattering (SAXS) and fluorescence resonance energy transfer (FRET) measurements we have determined the role of the H3 and H4 histone tails, independently, in stabilizing the nucleosome DNA terminal ends from unwrapping from the nucleosome core. We have perfo...

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Detalles Bibliográficos
Autores principales: Andresen, Kurt, Jimenez-Useche, Isabel, Howell, Steven C., Yuan, Chongli, Qiu, Xiangyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827064/
https://www.ncbi.nlm.nih.gov/pubmed/24265699
http://dx.doi.org/10.1371/journal.pone.0078587