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Beneficial Role of Rapamycin in Experimental Autoimmune Myositis

INTRODUCTION: We developed an experimental autoimmune myositis (EAM) mouse model of polymyositis where we outlined the role of regulatory T (Treg) cells. Rapamycin, this immunosuppressant drug used to prevent rejection in organ transplantation, is known to spare Treg. Our aim was to test the efficac...

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Detalles Bibliográficos
Autores principales: Prevel, Nicolas, Allenbach, Yves, Klatzmann, David, Salomon, Benoit, Benveniste, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827074/
https://www.ncbi.nlm.nih.gov/pubmed/24265670
http://dx.doi.org/10.1371/journal.pone.0074450