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Drosophila UTX Coordinates with p53 to Regulate ku80 Expression in Response to DNA Damage
UTX is known as a general factor that activates gene transcription during development. Here, we demonstrate an additional essential role of UTX in the DNA damage response, in which it upregulates the expression of ku80 in Drosophila, both in cultured cells and in third instar larvae. We further show...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827076/ https://www.ncbi.nlm.nih.gov/pubmed/24265704 http://dx.doi.org/10.1371/journal.pone.0078652 |