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Drosophila UTX Coordinates with p53 to Regulate ku80 Expression in Response to DNA Damage

UTX is known as a general factor that activates gene transcription during development. Here, we demonstrate an additional essential role of UTX in the DNA damage response, in which it upregulates the expression of ku80 in Drosophila, both in cultured cells and in third instar larvae. We further show...

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Detalles Bibliográficos
Autores principales: Zhang, Chengwan, Hong, Zehui, Ma, Wencui, Ma, Da, Qian, Yuchen, Xie, Wei, Tie, Feng, Fang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827076/
https://www.ncbi.nlm.nih.gov/pubmed/24265704
http://dx.doi.org/10.1371/journal.pone.0078652