Functional Analysis of a Breast Cancer-Associated FGFR2 Single Nucleotide Polymorphism Using Zinc Finger Mediated Genome Editing

Genome wide association studies have identified single nucleotide polymorphisms (SNP) within fibroblast growth factor receptor 2 (FGFR2) as one of the highest ranking risk alleles in terms of development of breast cancer. The potential effect of these SNPs, in intron two, was postulated to be due to...

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Detalles Bibliográficos
Autores principales: Robbez-Masson, Luisa J., Bödör, Csaba, Jones, J. Louise, Hurst, Helen C., Fitzgibbon, Jude, Hart, Ian R., Grose, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827080/
https://www.ncbi.nlm.nih.gov/pubmed/24265722
http://dx.doi.org/10.1371/journal.pone.0078839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827080/
https://www.ncbi.nlm.nih.gov/pubmed/24265722
http://dx.doi.org/10.1371/journal.pone.0078839

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