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Mammary Cells with Active Wnt Signaling Resist ErbB2-Induced Tumorigenesis

Aberrant activation of Wnt signaling is frequent in human malignancies. In normal epithelial tissues, including the breast, Wnt signaling is active only in a subset of cells, but it is unknown whether this subset of Wnt signaling-active cells is at increased risk of carcinogenesis. We created transg...

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Detalles Bibliográficos
Autores principales: Bu, Wen, Zhang, Xiang, Dai, Hua, Huang, Shixia, Li, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827100/
https://www.ncbi.nlm.nih.gov/pubmed/24265712
http://dx.doi.org/10.1371/journal.pone.0078720