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Reproducibility of the heat/capsaicin skin sensitization model in healthy volunteers

INTRODUCTION: Heat/capsaicin skin sensitization is a well-characterized human experimental model to induce hyperalgesia and allodynia. Using this model, gabapentin, among other drugs, was shown to significantly reduce cutaneous hyperalgesia compared to placebo. Since the larger thermal probes used i...

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Detalles Bibliográficos
Autores principales: Cavallone, Laura F, Frey, Karen, Montana, Michael C, Joyal, Jeremy, Regina, Karen J, Petersen, Karin L, Gereau, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827105/
https://www.ncbi.nlm.nih.gov/pubmed/24232380
http://dx.doi.org/10.2147/JPR.S53437